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Their stories inspire our mission. Your generosity helps move research forward.
More than 18 million people in the US have early age-related macular degeneration (AMD), facing the uncertainty of a future shaped by vision loss. It's the leading cause of blindness in people over the age of 55 in developed countries.
Researchers have discovered that genetics can play a role in AMD risk.
In 2005, three groups of researchers, including a team funded by the Foundation, discovered that a gene called Complement Factor H (CFH) is linked to at least 50 percent of all cases of AMD.
Since that breakthrough, researchers have found several other genes linked to AMD. CFH and many of the other AMD genes are involved in the innate immune system, which fights off infection. Scientists believe that overactivity of the innate immune system increases AMD risk.
Your support makes it possible for us to pursue the groundbreaking research needed and bring us closer to treatments and cures for people living with age-related macular degeneration.
Donations made through this page are unrestricted and support the Foundation Fighting Blindness' mission to advance research for all diseases within our portfolio, not solely age-related macular degeneration.